Mechanism of Blood Clotting
BLOOD CLOTTING MECHANISM
Calcium, Fibrinogen, Thromboplastin, are some of the substances needed before clotting occurs. The clotting process has the following steps:
- Thromboplastin is released when a blood vessel and tissue cells are damaged. This triggers off a number of reactions.
- Thromboplastin receives converted to Thrombin in the presence of Calcium ions.
- Thrombin convert's fibrinogen to fibrin (soft clot with fine threads).
- In the presence of Factor XIII, a hard clot is formed.
- The fibrin threads enmesh the cells, and this combination obstructs the opening and stops the bleeding.